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On a small plate spread salt.
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With lime wedges moisten rim of 6 ounce glasses.
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Dip glasses into salt.
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Place glasses into freezer to chill.
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In a pitcher combine tequila, orange juice, persimmon juice, agave (if using), lime juice and Cointreau.
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Remove glasses from freezer and serve margarita mixture over ice.
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Garnish with lime slices or orange zest.